Single cell design technology
Single Cell Omics: From Assay Design to Biomedical Application
Given the existence of cell heterogeneity, single cell analysis is undergoing a rapid expansion for life science and precision medicine. Recent numerous innovations in analytical platforms and instruments have re-energized the field and led to the emergence of single cell omics with high sensitivity …
Review article Recent development of hydrogen and fuel cell ...
Connecting a series of single cells to form a stack and collecting and transporting the generated current from one cell to the next cell. Therefore, durability and electrical and thermal conductivity are the required characteristics of BPs. b. Evenly distributing fuel gas on the anode surface and oxygen on the cathode surface.
The evolving single-cell and spatial technology landscape
Citation: The evolving single-cell and spatial technology landscape (2024, July ... Device malfunctions from continuous current lead to discovery that can improve design of microelectronic devices.
Single-cell technologies: From research to application
With powerful experimental single-cell technology and state-of-the-art big data analysis methods based on artificial intelligence, the molecular landscape at the …
The Intriguing Landscape of Single-Cell Protein Analysis
Based on the underlying method design, current single-cell protein analysis technology can be summarized into two major broad categories: one is targeted protein analysis technology represented by SCBC, mass cytometry, and single-cell immunoblotting technology, and another is non-targeted protein technology …
A review of the current state of single-cell proteomics and future ...
Another study we would like to highlight is the 2022 bioRxiv preprint work of Rosenberger et al., from the Mann group, where they describe a novel technology called single-cell deep visual proteomics (scDVP) and how it was used to resolve the context-dependent, spatial proteome of murine hepatocytes from a slice of a cell. This is a …
Single cell metabolism: current and future trends | Metabolomics
Single cell metabolomics is an emerging and rapidly developing field that complements developments in single cell analysis by genomics and proteomics. Major goals include mapping and quantifying the metabolome in sufficient detail to provide useful information about cellular function in highly heterogeneous systems such as tissue, ultimately with …
Single-Cell Genomics: Technology and Applications
Single-cell genomics is an emerging technique used to study individuality of cells by using omics approaches. The technique actually evolved after …
The Technology and Biology of Single-Cell RNA Sequencing
Historically, scRNA-seq was applied in situations in which the amount of biological material was a limiting factor, such as cells from early embryonic development (Tang et al., 2009, 2010) (Figure 1A) deed, scRNA-seq has provided important insights into global patterns of gene expression changes during the first stages of development …
Handbook of Single-Cell Technologies | SpringerLink
This book provides a brief overview of single-cell analysis using recent advanced technologies. The different sections cover different aspect of single cell analysis and applications with their advantages, limitations, …
Handbook of Single Cell Technologies | SpringerLink
Dr. Tuhin Subhra Santra received his PhD degree in Bio-Nano Electro Mechanical Systems (Bio-NEMS), especially for single cell analysis from the Institute of Nanoengineering and Microsystems (NEMS), National Tsing Hua University (NTHU), Taiwan in 2013, under the supervision of Professor Fan-Gang Tseng. Dr. Santra joined as an Assistant Professor at …
Single Cell Analysis: From Technology to Biology and Medicine
Single-cell analysis heralds a new era that allows "omics" analysis, notably genomics, transcriptomics, epigenomics and proteomics at the single-cell level. ... Single Cell Analysis: From Technology to Biology and Medicine Single Cell Biol. 2014;3(1):106. doi: 10.4172/2168-9431.1000106. Author Xinghua Pan 1 Affiliation 1 Department of …
Methods and applications for single-cell and spatial multi-omics
In this Review, we highlight advances in the fast-developing field of single-cell and spatial multi-omics technologies (also known as multimodal omics approaches), …
Single cell RNA-sequencing: A powerful yet still challenging technology …
Thus, the observable macroscopic ''average'' cannot outright be used as representative of the ''average cell''. Rather, it is the resulting emerging behaviour of the actions and interactions of many different cells. Single-cell RNA sequencing (scRNA-Seq) enables the comparison of the transcriptomes of individual cells.
Single-cell technologies: From research to application
With powerful experimental single-cell technology and state-of-the-art big data analysis methods based on artificial intelligence, the molecular landscape at the single-cell level can be revealed. With spatial …
Recent advances and challenges in single cell protein (SCP ...
1 · Single-cell protein (SCP) offers a sustainable solution. This review covers SCP production mechanisms, microbial and substrate choices, and advancements in …
Single-cell omics: Overview, analysis, and application in biomedical ...
Single-cell sequencing methods provide the highest resolution insight into cellular heterogeneity. Owing to their rapid growth and decreasing cost, they are now widely …
Single Cell Omics: From Assay Design to Biomedical Application
Given the existence of cell heterogeneity, single cell analysis is undergoing a rapid expansion for life science and precision medicine. Recent numerous innovations in analytical platforms and instruments have re-energized the field and led to the emergence of single cell omics with high sensitivity, throughput and multiplexity.
Applications of single-cell RNA sequencing in drug discovery and ...
Single-cell technologies, particularly single-cell RNA sequencing (scRNA-seq) methods, together with associated computational tools and the growing availability of public data resources, are ...
The Role of Single-Cell Technology in the Study and Control of ...
The advent of single-cell research in the recent decade has allowed biological studies at an unprecedented resolution and scale. In particular, single-cell analysis techniques such as Next-Generation Sequencing (NGS) and Fluorescence-Activated Cell Sorting (FACS) have helped show substantial links between cellular …
Single-cell analysis
This single cell shows the process of the central dogma of molecular biology, which are all steps researchers are interested to quantify (DNA, RNA, and Protein).. In the field of cellular biology, single-cell analysis and subcellular analysis [1] is the study of genomics, transcriptomics, proteomics, metabolomics and cell–cell interactions at the single cell …
Single-cell approaches in human microbiome research
This review describes a variety of recently developed single-cell approaches for studying the human microbiome and remaining ... Another limitation is the need to design specific FISH probes for the taxa of interest, limiting this method to known taxa. ... (Micro-SPLiT), have recently leveraged this technology for the study of bacterial …
Radiation Tolerant SRAM Cell Design in 65nm Technology
In this paper, eight different SRAM cells are studied and evaluated with a 65nm CMOS technology. The cells were designed with radiation-hardening-by-design approaches including schematic and layout techniques. The eight types of cells were placed into eight pages of an SRAM test chip. The alpha and proton irradiation demonstrated …
Use of single-cell technology to improve our understanding of …
The interaction between Mycobacterium tuberculosis, the agent of tuberculosis (TB), and its host cell, the macrophage, is multifaceted, dynamic, and involves multiple molecular partners.A better understanding of this interaction could help researchers manipulate the immune system in order to design host-targeted immunotherapies and/or …
Single-cell genomics technology: perspectives
Single-cell sequencing technology has also evolved over time, from processing dozens of cells to millions of cells simultaneously. New approaches to well-established models are being explored at the single-cell level in the field of medical sciences, and new rare cell types are being reported, one after another.
Engineering the next generation of cell-based therapeutics
Cell-based therapeutics are an emerging modality with the potential to treat many currently intractable diseases through uniquely powerful modes of action. Despite notable recent clinical and ...
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